The Big Ten Conference is a collegiate athletic conference in the United States.
Big Ten may also refer to:
- Big Ten Network, American sports network
 - Big Ten Tournament (disambiguation)
 - "Big Ten Inch Record", a song by Bull Moose Jackson
 - The Big 10, a mixtape by 50 Cent
 - "Big Ten", a song by English reggae musician Judge Dread
 
See also
- Big One (disambiguation)
 - Big Two (disambiguation)
 - Big Three (disambiguation)
 - Big Four (disambiguation)
 - Big Five (disambiguation)
 - Big Six (disambiguation)
 - Big Seven (disambiguation)
 - Big Eight (disambiguation)
 
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