GLA or Gla may refer to:
Entertainment
- GLA (album), by Scottish alternative rock band Twin Atlantic
 - Great Lakes Avengers, a fictional comic hero group
 
Science and technology
- Alpha-galactosidase, a glycoside hydrolase enzyme
 - GLA (gene), an encoding of the enzyme alpha-galactosidase A
 - Gla domain, a protein domain
 - Gamma-Linolenic acid, a fatty acid
 - Linde–Buzo–Gray algorithm (also called Generalized Lloyd Algorithm), a vector quantization algorithm
 
Other uses
- Gla, a Mycenaean fortification in Greece
 - Gross leasable area, used in Real Estate as the total floorspace in a project available for lease or rent
 - GLA University, in Mathura Uttar Pradesh, India
 - Gangmasters Licensing Authority, a British regulatory body
 - General lighthouse authority
 - Georgia Library Association
 - Ghana Library Association
 - Glamorgan, historic county in Wales, Chapman code
 - Glassbridge Enterprises, where GLA was its former NYSE ticker symbol
 - Glasgow Airport, IATA call-sign
 - Global Leadership Adventures, an international high school study abroad program
 - Great Lakes Airlines, an American airline
 - Greater London Authority
 - Guam Library Association
 - Mercedes-Benz GLA-Class
 - Scottish Gaelic, ISO 639-2 & ISO 639-3 language codes
 
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