SL2 may refer to:

Art and entertainment

• SL2 (musical group), British breakbeat hardcore group
• Stuart Little 2, a 2022 film

Maths and science

• Special linear Lie algebra ${\displaystyle {\mathfrak {sl}}_{2}}$
• the mathematical structure SL₂(F), a special linear group
• SL2 RNA, a non-coding RNA involved in trans splicing in lower eukaryotes
• Skylab 2 (SL-2), a NASA space mission

Technology and transport

• Leicaflex SL2, a mechanical reflex camera
• Canon EOS 200D, or Rebel SL2, a digital reflex camera
• Schütte-Lanz SL2, an airship used in WWI
• SL2, car in the Saturn S series
• SL2 (MBTA bus), Boston bus line
• Skylab 2 (SL-2), a NASA space mission

Other uses

• SL postcode area, the Slough postal region covering Farnham, Great Britain
• Situational Leadership II, a leadership theory developed by Paul Hersey
• Super League Greece 2 Greece's 2nd Division football championship