| 2021 Winston-Salem Open | |
|---|---|
| Date | August 21–28 | 
| Edition | 52nd | 
| Category | ATP Tour 250 Series | 
| Draw | 48S / 16D | 
| Surface | Hard / outdoor | 
| Location | Winston-Salem, North Carolina, U.S. | 
| Venue | Wake Forest University | 
| Champions | |
| Singles | |
|  Ilya Ivashka | |
| Doubles | |
|  Marcelo Arévalo /  Matwé Middelkoop | |
The 2021 Winston-Salem Open was a men's tennis tournament played on outdoor hard courts. It was the 52nd edition of the Winston-Salem Open (as successor to previous tournaments in New Haven and Long Island), and part of the ATP Tour 250 Series of the 2021 ATP Tour. It took place at Wake Forest University in Winston-Salem, North Carolina, United States, from August 21 through August 28, 2021. It was the last event on the 2021 US Open Series before the 2021 US Open.[1]
Champions
Singles
 Ilya Ivashka def. Ilya Ivashka def. Mikael Ymer, 6–0, 6–2 Mikael Ymer, 6–0, 6–2
Doubles
 Marcelo Arévalo / Marcelo Arévalo / Matwé Middelkoop def. Matwé Middelkoop def. Ivan Dodig / Ivan Dodig / Austin Krajicek, 6–7(5–7), 7–5, [10–6] Austin Krajicek, 6–7(5–7), 7–5, [10–6]
Points and prize money
Point distribution
| Event | W | F | SF | QF | Round of 16 | Round of 32 | Round of 48 | Q | Q2 | Q1 | 
| Singles | 250 | 150 | 90 | 45 | 20 | 10 | 0 | 5 | 3 | 0 | 
|---|---|---|---|---|---|---|---|---|---|---|
| Doubles | 0 | — | — | — | — | — | 
Prize money
| Event | W | F | SF | QF | Round of 16 | Round of 32 | Round of 48 | Q2 | Q1 | 
| Singles | $96,505 | $56,000 | $32,350 | $18,740 | $10,740 | $6,500 | $3,950 | $1,840 | $920 | 
| Doubles* | $40,600 | $20,800 | $11,280 | $6,450 | $3,780 | — | — | — | — | 
*per team
Singles main-draw entrants
Seeds
| Country | Player | Rank1 | Seed | 
|---|---|---|---|
|  ESP | Pablo Carreño Busta | 12 | 1 | 
| .svg.png.webp) BEL | |||
|  GBR | Dan Evans | 28 | 3 | 
|  HUN | Márton Fucsovics | 37 | 4 | 
|  KAZ | Alexander Bublik | 38 | 5 | 
|  CRO | Marin Čilić | 39 | 6 | 
|  GEO | |||
| .svg.png.webp) AUS | |||
|  GER | Jan-Lennard Struff | 47 | 9 | 
|  ARG | Federico Delbonis | 48 | 10 | 
|  ESP | Albert Ramos Viñolas | 49 | 11 | 
|  FRA | Benoît Paire | 50 | 12 | 
|  USA | Frances Tiafoe | 51 | 13 | 
|  FRA | Richard Gasquet | 53 | 14 | 
|  ESP | Carlos Alcaraz | 55 | 15 | 
|  GER | Dominik Koepfer | 59 | 16 | 
1 Rankings are as of August 16, 2021 [2]
Other entrants
The following players received wildcards into the singles main draw:
The following player received entry using a protected ranking into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Withdrawals
- Before the tournament
 Kevin Anderson → replaced by Kevin Anderson → replaced by Arthur Rinderknech Arthur Rinderknech
 Pablo Andújar → replaced by Pablo Andújar → replaced by Marco Cecchinato Marco Cecchinato
 Nikoloz Basilashvili → replaced by Nikoloz Basilashvili → replaced by Pierre-Hugues Herbert Pierre-Hugues Herbert
 Aljaž Bedene → replaced by Aljaž Bedene → replaced by Tennys Sandgren Tennys Sandgren
 Laslo Đere → replaced by Laslo Đere → replaced by Mikael Ymer Mikael Ymer
.svg.png.webp) David Goffin → replaced by David Goffin → replaced by Eduardo Nava Eduardo Nava
 Lloyd Harris → replaced by Lloyd Harris → replaced by Norbert Gombos Norbert Gombos
.svg.png.webp) Nick Kyrgios → replaced by Nick Kyrgios → replaced by Noah Rubin Noah Rubin
 Adrian Mannarino → replaced by Adrian Mannarino → replaced by Thiago Monteiro Thiago Monteiro
.svg.png.webp) John Millman → replaced by John Millman → replaced by.svg.png.webp) Max Purcell Max Purcell
 Yoshihito Nishioka → replaced by Yoshihito Nishioka → replaced by Facundo Bagnis Facundo Bagnis
 Miomir Kecmanović → replaced by Miomir Kecmanović → replaced by Radu Albot Radu Albot
 Tommy Paul → replaced by Tommy Paul → replaced by Andreas Seppi Andreas Seppi
 Lorenzo Sonego → replaced by Lorenzo Sonego → replaced by Yosuke Watanuki Yosuke Watanuki
Doubles main-draw entrants
Seeds
| Country | Player | Country | Player | Rank1 | Seed | 
|---|---|---|---|---|---|
|  POL | Łukasz Kubot |  BRA | Marcelo Melo | 37 | 1 | 
|  FRA | Nicolas Mahut |  FRA | Fabrice Martin | 40 | 2 | 
|  RSA | Raven Klaasen |  JPN | Ben McLachlan | 52 | 3 | 
|  ITA | Simone Bolelli |  ARG | Máximo González | 60 | 4 | 
1 Rankings are as of August 16, 2021
Other entrants
The following pairs received wildcards into the doubles main draw:
Withdrawals
- Before the tournament
 Ivan Dodig / Ivan Dodig / Jamie Murray → replaced by Jamie Murray → replaced by Ivan Dodig / Ivan Dodig / Austin Krajicek Austin Krajicek
 Marcel Granollers / Marcel Granollers / Horacio Zeballos → replaced by Horacio Zeballos → replaced by Oliver Marach / Oliver Marach / Philipp Oswald Philipp Oswald
 Wesley Koolhof / Wesley Koolhof / Jean-Julien Rojer → replaced by Jean-Julien Rojer → replaced by Ariel Behar / Ariel Behar / Gonzalo Escobar Gonzalo Escobar
 Kevin Krawietz / Kevin Krawietz / Horia Tecău → replaced by Horia Tecău → replaced by Tomislav Brkić / Tomislav Brkić / Nikola Ćaćić Nikola Ćaćić
.svg.png.webp) John Peers / John Peers / Filip Polášek → replaced by Filip Polášek → replaced by Marcus Daniell / Marcus Daniell / Marcelo Demoliner Marcelo Demoliner
 Tim Pütz / Tim Pütz / Michael Venus → replaced by Michael Venus → replaced by.svg.png.webp) Luke Saville / Luke Saville /.svg.png.webp) John-Patrick Smith John-Patrick Smith
 Rajeev Ram / Rajeev Ram / Joe Salisbury → replaced by Joe Salisbury → replaced by Marcelo Arévalo / Marcelo Arévalo / Matwé Middelkoop Matwé Middelkoop

