Nicu is both a masculine Romanian given name and a Romanian surname. Notable people with the name include:
Given name:
- Nicu Ceaușescu (1951–1996), Romanian communist
 - Nicu Constantin (1938–2009), Romanian actor
 - Nicu Constantinescu (1840–1905), Romanian politician
 - Nicu Covaci (born 1947), Romanian painter and musician
 - Nicu Paleru (born 1973), Romanian Gypsy musician
 - Nicu Porsena (Ionescu) (1892–1971), Romanian writer
 - Nicu Stoian (born 1957), Romanian volleyball player
 - Nicu Vlad (born 1963), Romanian weightlifter
 
Surname:
- Epaminonda Nicu (born 1979), Romanian footballer
 - Maximilian Nicu (born 1982), German-Romanian footballer
 
See also
- Neonatal intensive care unit (NICU)
 - Neurosurgery intensive care unit (NICU)
 - Nicu's Spoon Theater Company, American theater company
 
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